Polio Virus detected in London sewage samples – WHO

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The World Health Organisation and British health officials said, Wednesday that a type of poliovirus derived from vaccines has been detected in London sewage samples, adding that more analysis was underway.

No human cases of polio have been found in Britain, where the crippling disease was fully eradicated two decades ago.

The WHO said in a statement that “type 2 vaccine-derived polio virus (VDPV2)” had been found in environmental samples in the British capital.

“It is important to note that the virus has been isolated from environmental samples only,” it said, stressing that “no associated cases of paralysis have been detected.” 

But it warned, “any form of poliovirus anywhere is a threat to children everywhere.”

A massive global effort has in recent decades come close to wiping out polio, a crippling and potentially fatal viral disease that mainly affects children under the age of five.

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Cases have decreased by 99 percent since 1988, when polio was endemic in 125 countries and 350,000 cases were recorded worldwide.

The wild version of the virus now exists only in Afghanistan and Pakistan, but a type of vaccine that contains small amounts of weakened but live polio still causes occasional outbreaks elsewhere.

Oral polio vaccine (OPV) replicates in the gut and can be passed to others through faecal-contaminated water – meaning it won’t hurt the child who has been vaccinated, but could infect their neighbours in places where hygiene and immunisation levels are low.

While weaker than wild polio virus, this variant can cause serious illness and paralysis in people not vaccinated against the disease.

Polio immunisation coverage in London stands at nearly 87 percent, the WHO said. 

Globally, there were 959 confirmed cases of VDPV2 in 2020, according to the WHO.

The UN’s health agency has called for OPV to be phased out worldwide and replaced with inactivated polio vaccine (IPV).

Britain stopped using OPV in 2004, and British health authorities said it was likely that the virus found in the sewage samples had been imported by someone who was recently vaccinated with it abroad.

The UK Health Security Agency (UKHSA) said the virus isolates had been found in “multiple sewage samples collected from the London Beckton Sewage Treatment Works between February and June 2022.”

The plant covers a large swathe of north and east London that is home to around four million people.

A couple of poliovirus isolates are detected each year on average in UK sewage samples, but they tend to be unrelated, health authorities said, warning that in this case the isolates were “genetically related”.

“This has prompted the need to investigate the extent of transmission of this virus in northeast London,” UKHSA said.

“The environmental surveillance is being enhanced in an attempt to assess the extent of VDPV2 transmission and identify areas for targeted action.”